Description: Monolix is the most advanced and simple solution for non-linear mixed effects modeling (NLME) for pharmacometrics. It is based on the SAEM algorithm and provides robust, global convergence even for complex PK/PD models. Monolix is used for preclinical and clinical population PK/PD modeling and for Systems Pharmacology. Monolix enjoys a large user community. Monolix is widely used by academia, the pharmaceutical industry as well as the US regulatory agencies.

Advanced Statistical Methodologies
Reliable convergence for all type of data is a centerpiece in population PKPD modeling, which is why Lixoft pioneered in collaboration with Inria the SAEM algorithm.

Automated generation of diagnostic tests
Monolix automatically generates a full set of diagnostic plots even for complex PK/PD models. For example, you can instantaneously create the Visual Predictive Check, split by any patient subgroup you would want to investigate.

Increased productivity and quality
Efficient C++ solver package, standardized model language with Mlxtran, PK/PD model library and integrated software all contribute to better productivity and quality.

Very easy to use with its GUI
Our solutions are designed for ease of use. Monolix can be used via a graphical interface or command lines for powerful scripting. This means less programming for you and more focus on exploring models and pharmacology to deliver in time to your customers.

Key features:
Support of all relevant data types and statistical features
Monolix covers a wide range of data types and statistical features for population PK/PD modeling. For all cases the right statistical methodology has been developed and published for reference.

Monolix covers:
Continuous, categorical, count and repeated time to event data.
Mixture models and mixtures of models.
Inter-occasion variability with any number of levels.
Proper handling of BLQ data.
Normal, lognormal, logit, probit and user defined distributions for the individual parameters.

Release Name: monolix Suite 2023R1 (x64)
Size: 193.6 MB
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Description: EF Commander is a complex and multi-featured file manager that a wide range of users, from beginners to professionals, will find easy to use. It is the result of many requests received by the author. The first version was written in 1994, under the OS/2 operating system using Presentation Manager, as a personal replacement for the old DOS program Norton Commander™. In 1996 it was ported to the 32-bit Microsoft Windows™ operating system.

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Release Name: EF Commander 23.03 Multilingual
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ON1 Photo RAW (was ON1 Photo) is the lightning fast raw processor, photo editor, and plug-in collection all in one app photographers have been asking for. Unlike the current class of raw-based photo editors requiring catalogs, bouncing between apps for editing, and a subscription ecosystem, ON1 Photo RAW features a new, modern raw processing engine, tuned for today’s sensors and graphics chips. Combined with our current set of tools, the next generation of ON1 Photo 10, will continue to work where you want, as a standalone app, a plug-in for Adobe Photoshop and Lightroom, or a host app for other editing apps.

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Version 17.1.1:

• Release notes were unavailable when this listing was updated.

macOS 10.15 or later

Release Name: ON1 Photo RAW 2023.1 v17.1.1.13585
Size: 3.1 GB
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Version 1.9.2.1849:

• Release notes were unavailable when this listing was updated.

macOS 10.10 or later

Release Name: ImageRanger Pro Edition 1.9.2.1849
Size: 105.7 MB
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ON1 Resize (was Perfect Resize) is the industry standard for photo enlargements. Use Genuine Fractals powered algorithms for optimizing clarity and detail for different image types. Get the best quality enlargements for your photos, whether taken with a DSLR or your mobile device.

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Version 17.1.1:

• Release notes were unavailable when this listing was updated.

macOS 10.15 or later
Apple Silicon or Intel Core processor

Release Name: ON1 Resize AI 2023.1 v17.1.1.13585
Size: 648.8 MB
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